49ers Schedule 2025 2025 Season. View future san francisco 49ers schedules and opponents at fbschedules.com. Here is who the san francisco 49ers will play at home and on the road during the 2025 nfl season after securing last place in the nfc west in 2024.

The san francisco 49ers’ regular season began on september 9, 2024, and will end on january 5, 2025. The schedule includes the opponents, dates, and results.